Ivanov V, Goc A, Ivanova S, Niedzwiecki A, Rath M
Infectious Diseases: Research and Treatment. January 2021. Volume 14: 1–7
Background: Angiotensin-converting enzyme II or ACE2 is an integral membrane protein present on many types of cells, including vascular endothelial cells and lung alveolar epithelial cells. This receptor serves as the entry point for SARS-coronaviruses (SARS-CoVs), including a novel coronavirus 2019-nCoV. Limited availability of these receptors can thwart cellular entry of this virus.